ISSN: 2251-8363    eISSN: 2251-8819  
J Nephropathol. 2012;1(1):17-22.
doi:10.5812/jnp.5
PMID: 24475382
PMCID: PMC3886164

Scopus id: 84866756515

Short Review Article

Turmeric: Reemerging of a neglected Asian traditional remedy

Parviz Khajehdehi 1 *

1 Shiraz Nephro-Urology Research Center and Department of Nephrology, Shiraz University of Medical Sciences, Shiraz, Iran.
*Corresponding author: Porf. Parviz Khajehdehi; Shiraz Nephro-Urology Research Center (SNURC) and Department of Nephrology, Shiraz University of Medical Sciences, Shiraz, Iran. Telephone: 00987116270607, Fax: 00987116260226, Email: khajehdehi@gmail.com

Abstract

Context: Turmeric (Curcuma longa) is a wild plant of the ginger family native to tropical South Asia.

Evidence Acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched.

Results: Emerging evidence indicate that turmeric/curcumin inhibits cytokines and TGF-β production. From the various factors involved in the genesis of chronic kidney disease and pathogenesis of primary and secondary glomerulonehritis, TGF-β has emerged as a key factor in the cascade of events. Leading to glomerulosclerosis, tubulointerstitial fibrosis and end-stage renal disease.

Conclusions: considering the inhibitory effect of turmeric/curcumin on cytokines and TGF-β, it seems wise to assume that supplementary turmeric/curcumin might be a candidate remedy for chronic kidney disease and possibly prevention of subsequent end stage renal disease.

Implication for health policy/practice/research/medical education:

Turmeric (Curcuma longa) is a wild plant of the ginger family native to tropical South Asia. This review is addressed to inhibitory effect of turmeric/curcumin on cytokines and TGF-β. It is possible that supplementary turmeric/curcumin might be a candidate remedy for chronic kidney disease and possibly prevention of subsequent end-stage renal disease.

Please cite this paper as: Khajehdehi P. Turmeric: Reemerging of a neglected Asian traditional remedy. J Nephropathology. 2012; 1(1):17-22. DOI: 10.5812/jnp.5

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