Implication for health policy/practice/research/medical education:
The prevalence and clinical picture of IgA nephropathy (IgAN) varies from region to region. There is a limited knowledge
about the morphological features of this disease according to recent Oxford-MEST classification in Iran and Middle East.
In this study higher prevalence of segmental glomerulosclerosis and interstitial fibrosis/tubular atrophy as the two of four
variables of this classification in male patients further attests that male gender is a risk factor in this kind of disease. Significant
correlation between serum creatinine and extracapillary proliferation was in an agreement with previous studies and was suggested
for the probable accommodation of crescent as a new variable in the MEST system.
Please cite this paper as: Nasri H, Mortazavi M, Ghorbani A, Shahbazian H, Kheiri S, Baradaran A, Emami-Naieni A, Saffari M,
Mardani S, Momeni A, Madihi Y, Baradaran-Ghahfarokhi M, Rafien-Kopaie M, Hedayati P, Baradaran S, Ardalan MR , Sajjadieh
S, Assarzadegan N, Ahmadi Soleimani SM, Tamadon MR. Oxford-MEST classification in IgA nephropathy patients:
A report from Iran. J Nephropathology. 2012; 1(1): 31-42. DOI: 10.5812/jnp.7