J Nephropathol. 2016;5(4):139-143.
doi: 10.15171/jnp.2016.26
PMID: 27921026
PMCID: PMC5125061
Scopus id: 84983249695
  Abstract View: 1572
  PDF Download: 810

Original Article

A study on the association of diabetic dermopathy with nephropathy and retinopathy in patients with type 2 diabetes mellitus  

Mahmoud Mirhoseini 1 * , Nasrin Saleh 2, Ali Momeni 3, Fatemeh Deris 4, Majid Asadi-Samani 2

1 Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Students Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran
3 Cellular and Molecular Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
4 Social Health Determinants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
*Corresponding author: Mahmoud Mirhoseini, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran; Email: seidmahmood_mirhoseini@yahoo.com

Abstract

Background: Diabetic dermopathy is one of the most prevalent skin complications in diabetes
patients. Some studies have pointed to association of diabetic dermopathy with retinopathy
and nephropathy in patients with type 2 diabetes as microangiopathy presentations, but no
rigorous study has been conducted to confirm this association.

Objectives: This study investigated association of diabetic dermopathy with nephropathy and
retinopathy in patients with type 2 diabetes referring specialty clinic of Shahrekord.

Patients and Methods: This descriptive, cross-sectional study was conducted on 102
type 2 diabetes patients with dermopathy referring clinic constantly or as outpatient.
Dermatological and ophthalmological examinations and examination for nephropathy were
done for all patients. Demographic data and results of examinations and patients history,
and biochemical tests were gathered and recorded by researcher developed checklists.

Results: Mean age of patients was 83.8 2.60 years, of whom 64 (63.7%) were female and
37.3% were male. Prevalence of retinopathy in patients was 4.31% and nephropathy 3.33%.
In this study, significant associations of diabetic dermopathy with diabetic nephropathy
(P = 0.001), with retinopathy (P < 0.001), age (P < 0.001), duration of diabetes (P = 0.001),
and also with glycosylated hemoglobin (P < 0.01) was detected. No significant association
between diabetic dermopathy and other studied variables was seen (P > 0.05).

Conclusions: Results of this study confirm the association of diabetic dermopathy with
retinopathy and nephropathy in patients with type 2 diabetes. Since dermopathy is usually
developed before retinopathy and nephropathy, dermopathy could be used as a clinical
finding in early diagnosis and prevention of retinopathy and nephropathy in diabetes
patients.



Implication for health policy/practice/research/medical education:


Diabetic dermopathy is prevalent and generally takes place before retinopathy and nephropathy. Few studies have so far
investigated the association between systemic complications of diabetes such as retinopathy and nephropathy and obtained
inconsistent findings. Since diabetic dermopathy takes place before retinopathy and nephropathy if the association between
diabetic dermopathy with retinopathy and nephropathy in diabetic patients is confirmed, early diagnosis of dermopathy could
be to prevent retinopathy and nephropathy. This study confirms the association of diabetic dermopathy with retinopathy and
nephropathy and suggests dermopathy as a usable clinical finding in early diagnosis of retinopathy and nephropathy in patients
with type 2 diabetes.

Please cite this paper as: Mirhoseini M, Saleh N, Momeni A, Deris F, Asadi-Samani M. A study on the association of diabetic
dermopathy with nephropathy and retinopathy in patients with type 2 diabetes mellitus. J Nephropathol. 2016;5(4):139-143.
DOI: 10.15171/jnp.2016.26.

 
 
First name
 
Last name
 
Email address
 
Comments
 
Security code


Article Viewed: 1572

Your browser does not support the canvas element.


PDF Downloaded: 810

Your browser does not support the canvas element.

First published online: 26 Jul 2016
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)