Divya Asti, Nicholas Fuca, Jiyoung Wong, Bindu Madhavi Mudduluru, Elie El-Charabaty
*1 Department of Internal Medicine, Department of Nephrology, Staten Island University hospital, Northwell Health, NY, United States
Abstract
Background: Guillain-Barré syndrome (GBS) is an autoimmune disease damaging
the peripheral nervous system. It commonly presents as rapidly progressing bilateral
symmetrical motor weakness. There has been known association of syndrome of
inappropriate antidiuretic hormone (SIADH) in patients with GBS though it is rare.
Case Presentation: We report a patient with rare clinical presentation of SIADH before the
onset of motor deficits in GBS.
Conclusions: SIADH as an initial finding in patients with GBS is very rare. This case
report emphasizes the importance of early detection of SIADH in GBS to avoid delay in
treatment.
Implication for health policy/practice/research/medical education:
Our case report emphasizes that SIADH could precede the development of profound motor deficit in patients with GuillainBarré
syndrome. Physicians should be aware of this rare presentation to prevent delays in diagnosis and proper treatment.
Please cite this paper as:Asti D, Fuca N, Wong J, Mudduluru BM, El-Charabaty E. Syndrome of inappropriate antidiuretic hormone
as the initial presentation in Guillain-Barré syndrome. J Nephropathol. 2018;7(3):207-209. DOI: 10.15171/jnp.2018.42.