J Nephropathol. 2019;8(1): e2.
doi: 10.15171/jnp.2019.02
  Abstract View: 533
  PDF Download: 475

Review

Protective effects of olive in renal failure; a review on current knowledge

Esmaeel Babaeenezhad 1,2, Hassan Ahmadvand 2,3, Reza Mohammadrezaei Kkorramabadi 3 * , Shahrokh Bagheri 3, Peyman Khosravi 3, Parisa Jamor 4

1 Department of Cardiology, Madani Heart Center, Lorestan University of Medical Sciences, Khorramabad, Iran
2 Department of Biochemistry, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
3 Razi Herbal Researches Center, Lorestan University of Medical Sciences, Khorramabad, Iran
4 Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
*Corresponding author: Reza Mohammadrezaei Kkorramabadi; Email: Email: reza.mr@chmail.ir

Abstract

Context: The pathogenesis of renal damage as a risk factor of renal failure can be due to oxidative stress resulting from an imbalance between the production of free radicals and antioxidants. Therefore, antioxidant therapy can be a good strategy to decrease the effects of such diseases. Hence, the aim of this review was to evaluate the protective effect of olive oil as an herb rich in antioxidant compounds on kidney damage in previous studies.

Evidence Acquisitions: Present review is based on scrutinizing the contents of relevant papers searched in PubMed, Google Scholar, EBSCO, Embase, directory of open access journals (DOAJ), Web of Science and Scopus.

Results: Numerous studies have introduced herbal treatments, being rich sources of antioxidants, as appropriate alternatives for several diseases, including renal damage, when considering the pathogenesis of the diseases. The olive has also been recommended as a plant that has different therapeutic effects, and its therapeutic effects on the kidneys are mentioned in several studies, including the reduction of renal damage parameters and an increase in the antioxidant power of enzymes in the body.

Conclusions: Considering the numerous studies on animal models, particularly rats and renal cell lines, olive oil can be used as a reliable method for the treatment of various kidney damages. However, further studies are also recommended in humans.

Implication for health policy/practice/research/medical education:

Today, the need for plant derived compounds to treat diseases is felt more and more due to the lower side effects. On the other hand, studies have shown that medicinal plants, especially olives, have an effect on kidney disease.

Please cite this paper as: Babaeenezhad E, Ahmadvand H, Mohammadrezaei Kkorramabadi R, Bagheri S, Khosravi P, Jamor P. Protective effects of olive in renal failure; a review on current knowledge. J Nephropathol. 2019;8(1):e02. doi: 10.15171/ jnp.2019.02.

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Submitted: 14 Feb 2018
Accepted: 10 Jun 2018
First published online: 29 Jun 2018
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