J Nephropathol. 2019;8(2): e13.
doi: 10.15171/jnp.2019.13
  Abstract View: 221
  PDF Download: 188

Original Article

The effect of the omega-3 supplement on uremic pruritus in hemodialysis patients; a double-blind randomized controlled clinical trial

Shokouh Shayanpour 1, Seyed Seyfollah Beladi Mousavi 1,2, Parastoo Lakhaye Rizi 1 * , Bahman Cheraghian 2

1 Department of Nephrology, Imam Khomeini Hospital, Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Department of Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
*Corresponding author: Parastoo Lakhaye Rizi, Email: Email: parastoo5891@gmail.com

Abstract

Background: Chronic kidney disease (CKD) and uremic syndrome cause malfunction in most of organs including skin.

Objectives: This study was designed to investigate the effects of omega-3 supplement on uremic pruritus in chronic hemodialysis patients.

Patients and Methods: In this double-blind randomized controlled clinical trial study (#IRCT cod; 29363; http://irct.ir/trial/29363), the effect of the omega-3 supplement on uremic pruritus was assessed in 64 chronic hemodialysis patients (using standard 5-D itch scale questionnaire). Patients were surveyed at the hemodialysis department of Imam Khomeini and Razi hospitals in Ahvaz city, Iran.

Results: We found that the mean score of itching degree in the intervention and the placebo groups decreased from 3.56 to 1.72 (P<0.001) and 3.63 to 3.09 (P<0.05) respectively.

Conclusions: In our study, the omega-3 supplement could reduce uremic pruritus in chronic hemodialysis patients.

Implication for health policy/practice/research/medical education:

In a double-blind randomized controlled clinical trial, we found omega-3 supplement could reduce uremic pruritus in chronic hemodialysis patients.

Please cite this paper as: Shayanpour S, Beladi Mousavi SS, Lakhaye Rizi P, Cheraghian B. The effect of the omega-3 supplement on uremic pruritus in hemodialysis patients; a double-blind randomized controlled clinical trial. J Nephropathol. 2019;8(2):e13. DOI: 10.15171/ jnp.2019.13.

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Submitted: 10 Jul 2018
Accepted: 20 Oct 2018
First published online: 27 Nov 2017
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