J Nephropathol. 2019;8(2): e19.
doi: 10.15171/jnp.2019.19
  Abstract View: 366
  PDF Download: 344

Photonephropathol

Steroid-resistant minimal change disease with ballooned podocytes

Francesco Fortarezza 1 * , Maria Grazia Fiore 1, Michele Rossini 2, Domenico Piscitelli 1, Loreto Gesualdo 2, Leonardo Resta 1, Roberta Rossi 1

1 Department of Emergency and Organ Transplantation , Pathology Division, Medical School, University of Bari, Bari, Italy
2 Department of Emergency and Organ Transplantation, Nephrology Division, Medical School, University of Bari, Bari, Italy
*Corresponding author: Francesco Fortarezza, Email: Email: francescofortarezza.md@gmail.com

Implication for health policy/practice/research/medical education:

Minimal change disease (MCD) is a disorder affecting the kidneys which causes a nephrotic syndrome. The pathogenesis is unclear and genetic, immunological factors and infections have been studied as a possible trigger. We describe a case of steroid-resistent MCD with an unusual pattern of podocyte damage, occurred in children with coeliac disease, CMV infection and a variant in heterozygosis for the ACTN4 gene.

Please cite this paper as: Fortarezza F, Fiore MG, Rossini M, Piscitelli D, Gesualdo L, Resta L, et al. Steroid-resistant minimal change disease with ballooned podocytes. J Nephropathol. 2019;8(2):e19. DOI: 10.15171/jnp.2019.19.

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Submitted: 02 Mar 2017
Accepted: 04 Sep 2017
First published online: 27 Sep 2017
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