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J Nephropathol. 2020;9(4): e41.
doi: 10.34172/jnp.2020.41

Scopus ID: 85085277130
  Abstract View: 340
  PDF Download: 170

Original Article

The relationship between microalbuminuria, overweight and obesity

Roya Hemayati 1 ORCID logo, Fatemeh Kaseb 2 ORCID logo, Akram Ghadiri-anari 3 ORCID logo, Fatemeh Yosefi 4 * ORCID logo

1 Department of Internal Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2 School of Para-Medicine, Shahid Sadoughi University of medical Sciences, Yazd, Iran
3 Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4 Shahid Sadoughi University of Medical Sciences, Yazd, Iran
*Corresponding author: Fariba Yosefi, Email: f.yousefi44@yahoo.com, faribayosefi2012@gmail.com

Abstract

Introduction: Diabetes, hypertension and obesity are associated with endothelial dysfunction. The first sign of endothelial dysfunction is microalbuminuria.

Objectives: The aim of this study was to measure urine albumin to creatinine ratio in obese patients without diabetes and with normal blood pressure.

Patients and Methods: In this cross-sectional study, 200 adults were chosen with body mass index (BMI) ≥25 kg/m2 . Anthropometry measurements [BMI and waist to hip ratio (WHR)] and biochemical tests were performed. Data were analyzed using chi-square test, analysis of variance (ANOVA), and Pearson’s correlation coefficient.

Results: Among 200 obese people, microalbuminuria was seen in 22 individuals (11%). The prevalence of microalbuminuria was positively increased with increasing of BMI (P= 0.04). Moreover, microalbuminuria was significantly higher in people with WHR >1 (P=0.02).

Conclusion: Through this study, we detected the association of microalbuminuria with BMI and WHR. Therefore, efforts must be conducted to reduce obesity through lifestyle changes and regular exercise.

Keywords: Obesity, Albuminuria, Body mass index, Waist to hip ratio, Endothelial dysfunction, Obesity-related glomerulopathy, Chronic kidney disease, Focal segmental glomerulosclerosis

Implication for health policy/practice/research/medical education:

In a cross-sectional study, on 200 adults with body mass index ≥ 25 kg/m2 , microalbuminuria in 11% of individuals was seen.

Please cite this paper as: Hemayati R, Kaseb F, Ghadiri-anari A, Yosefi F. The relationship between microalbuminuria, overweight and obesity. J Nephropathol. 2020;9(4):e41. DOI: 10.34172/jnp.2020.41.

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Submitted: 09 Jan 2020
Accepted: 23 Apr 2020
ePublished: 17 May 2020
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