Implication for health policy/practice/research/medical education:
In the last three decades, a variety of clinical manifestations involving almost
all organs and tissues (cardiac, pulmonary, neurological, renal, cutaneous, haematologic,
gastrointestinal, ocular, skeletal and endocrinologic), have been described
associated with antiphospholipid antibodies (aPL) . Nevertheless, the
exact mechanism underlying the pathogenesis of aPL-mediated damage has
been poorly recognized. Inflammatory mechanisms beyond thrombosis have
been proposed in some clinical presentations, suggesting a role for immunomodulation
in therapeutic strategy.
Please cite this paper as: Serrano F.Antiphospholipid Syndrome: A complex disease.J
Nephropathology. 2013; 2(1): 73-74. DOI: 10.5812/nephropathol.8999