*Corresponding Author: *Corresponding author:Dr. Rodrigo Alfaro, 615 S Preston St, Louisville, KY 40202. Tel/Fax: +01 915 603 2959, , Email:
rjalfa01@louisville.edu
Abstract
Background: Acute tubular necrosis and pigment induced kidney injury are well described consequences of cocaine abuse. However, acute interstitial nephritis associated with cocaine use has been previously reported in only three patients.
Case presentation: We present the case of a 49-year-old man who developed acute kidney injury from biopsy-proven interstitial nephritis after nasal insufflation of cocaine. Unlike prior reports, our patient remained non-oliguric and did not require renal replacement therapy.
Conclusions: Interstitial nephritis should be considered as a potential cause of acute kidney injury associated with cocaine use. The approach to management of cocaine associated acute kidney injury (AKI) may be different in patients with interstitial nephritis than for those with tubular necrosis or pigment induced renal injury.
Implication for health policy/practice/research/medical education:
Interstitial nephritis should be considered as a potential cause of acute kidney injury associated with cocaine
use. The approach to management of cocaine associated acute kidney injury (AKI) may be different in patients
with interstitial nephritis than for those with tubular necrosis or pigment induced renal injury.
Please cite this paper as: Alfaro R, Vasavada N, Paueksakon P, Hernandez GT, Aronoff GR. Cocaine-induced
acute interstitial nephritis: A case report and review of the literature. J Nephropathology. 2013; 2(3): 204-209,
DOI: 10.12860/JNP.2013.33