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J Nephropathol. 2014;3(3): 109-113.
doi: 10.12860/jnp.2014.21
PMID: 25093159
PMCID: PMC4119326
Scopus ID: 84925043621
  Abstract View: 4947
  PDF Download: 1803

Case Report

Sirolimus-induced bronchiolitis obliterans organizing pneumonia in a kidney transplant recipient; a case report and review of literature

Behzad Einollahi, Jafar Aslani, Mehrdad Taghipour*, Mohsen Motalebi, Hamidreza Karimi-Sari

1 Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
*Corresponding Author: Corresponding author: Mehrdad Taghipour, MD; Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences. Tehran, Iran. , Email: mehrdadtaghipour@gmail.com

Abstract

Background: Sirolimus is immunosuppressive drug used to prevent rejection in kidney transplantation. Pulmonary problems are one of the serious complications which may be seen after administration of this drug and it is believed that it could be life threatening.

Case Presentation: Here in this paper we presented a 49-years-old man with bronchiolitis obliterans organizing pneumonia (BOOP) induced by chronic use of Sirolimus. The disease was diagnosed and successfully treated.

Conclusions: Sirolimus uses after kidney transplantation may lead to lung complications, especially BOOP, and the prompt diagnosis would allow earlier treatment.


Implication for health policy/practice/research/medical education:

Sirolimus is immunosuppressive drug used to prevent rejection in kidney transplantation. Pulmonary problems are one of the serious complications which may be seen after administration of this drug and it is believed that it could be life threatening.

Please cite this paper as: Einollahi B, Aslani J, Taghipour M, Motalebi M, Karimi-Sari H. Sirolimus-induced bronchiolitis obliterans organizing pneumonia in a kidney transplant recipient; a case report and review of literature. J Nephropathol. 2014; 3(3):109-113. DOI: 10.12860/jnp.2014.21

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