Ala Sh. Ali
1* 
, Huda A. Al-Taee
1, Thaeer J. Kadhim
21 Nephrology and Renal Transplantation Centre, The Medical City, Baghdad, Iraq
2 Department of Pathology, Al-Yarmook Teaching Hospital, Baghdad, Iraq
Abstract
Crescentic glomerulonephritis (GN) is a severe proliferative renal lesion with an aggressive clinical scenario. The occurrence of crescentic GN post-transplant is mainly related to the recurrence of the primary glomerular disease. De novo crescentic GN in renal allografts is rare. We present five patients diagnosed with crescentic GN post-transplantation during 10 years period. There were two males and three females with age range 20-50 years. Three cases were crescentic phenotypes of recurrent disease and two were de novo. The post-transplant time range was (7-144 months). Three patients lost their grafts and returned to dialysis. One patient had chronic allograft dysfunction and one patient died because of severe renal failure. Recurrent or de novo crescentic GN is not uncommon, especially in a live donor program. It leads to graft loss in most cases.