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J Nephropathol. 2022;11(1): e1.
doi: 10.34172/jnp.2022.01

Scopus ID: 85118106361
  Abstract View: 1461
  PDF Download: 577

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Autophagy and treatment of patients with COVID-19; which drugs target the autophagy pathway?

Elahe Aleebrahim-Dehkordi 1 ORCID logo, Shirin Saberianpour 2 ORCID logo, Ebrahim Soleiman-Dehkordi 1 ORCID logo, Dariush Hooshyar 3,4 ORCID logo, Zahra Mojtahedi 5 ORCID logo, Neda Kianpour 6 ORCID logo, Ali Hasanpour-Dehkordi 7* ORCID logo, Lillian Saberian 8 ORCID logo, Mohsen Akhavan Sepahi 9* ORCID logo

1 Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Vascular and Endovascular surgery Research Center, Mashhad University of Medical Science, Mashhad, Iran
3 Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
4 Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
5 Department of Health Care Administration and Policy, School of Public Health, University of Nevada Las Vegas, Las Vegas, Nevada, USA
6 Biohouse, Inland Norway University of Applied Sciences, Hamar, Hedmark, Norway
7 Social Determinants of Health Research Center, School of Allied Medical Sciences, Shahrekord University of Medical Sciences, Shahrekord, Iran
8 Independent researcher and Author, Medical Doctor, 151 Rosewell Avenue, Toronto, ON, Canada
9 Department of Pediatric Nephrology, School of Medicine, Qom University of Medical Sciences, Qom, Iran
*Corresponding Authors: *Corresponding authors: Ali Hasanpour-Dehkordi, Ph.D., Email; , Email: alihassanpourdehkordi@gmail.com; *Corresponding authors: Mohsen Akhavan Sepahi, Email; Akhavansepahimm@gmail.com, , Email: Makhavan@muq.ac.ir

Abstract



Implication for health policy/practice/research/medical education:

Autophagy is a way to create new cellular structures, clear cells invaded by microbes, and block accumulating proteins that can cause disease. Moreover, it can destroy all cellular organs and pathogens, including fungi, parasites, bacteria, and viruses, either randomly or selectively. Many research groups are examining a strategy to combat COVID-19. In particular, research is underway to identify drugs that can target autophagy in COVID-19 virus infection. Several known drugs are currently under clinical evaluation for the autophagy process, given that regulating autophagy is a way to combat COVID-19. This study introduces drugs that target the autophagy pathway.

Please cite this paper as: Aleebrahim-Dehkordi E, Saberianpour S, Soleiman-Dehkordi E, Hooshyar D, Mojtahedi Z, Kianpour N, Hasanpour-Dehkordi A, Saberian L, Akhavan Sepahi M. Autophagy and treatment of patients with COVID-19; which drugs target the autophagy pathway? J Nephropathol. 2022;11(1):e01. DOI: 10.34172/jnp.2022.01.


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Abstract View: 1462

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PDF Download: 577

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Submitted: 05 Apr 2020
Accepted: 10 Jan 2021
ePublished: 16 Jan 2021
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