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J Nephropathol. Inpress.
doi: 10.34172/jnp.2022.17219
  Abstract View: 906

Case Report

A rare presentation of extragonadal germ cell tumor; massive pericardial effusion with impending tamponade

Mahmoud Beheshti Monfared 1 ORCID logo, Hamid Ghaderi 1 ORCID logo, Zahra Ansari Aval 2* ORCID logo, Manouchehr Hekmat 1 ORCID logo, Seyedeh Adeleh Mirjafari 3 ORCID logo, Reza Beheshti Monfared 4 ORCID logo

1 Department of Cardiovascular Surgery, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Clinical Research and Development Center, Shahid Modarres Hospital, Department of Cardiac Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Department of Pediatrics, Ali-Asghar Children’s Hospital, Iran University of Medical Sciences, Tehran, Iran
4 Department of Anesthesiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Author: *Corresponding author: Zahra Ansari Aval, Email: Z.ansari@sbmu.ac.ir, , Email: zahraansariaval@gmail.com

Abstract

The clinical manifestations of extragonadal germ cell tumor (EGGCT) depend on its location and are often caused by compression on surrounding structures. Pericardial effusion is absolutely rare as an initial clinical manifestation for this tumor. We report a 31-year-old man presenting to the emergency department with dyspnea. Two-dimensional echocardiography revealed a massive pericardial effusion with impending tamponade. The patient was immediately transferred to the operating room where a cardiac surgeon drained bloody effusion. A mediastinal mass measuring 173×105×105 mm was accidentally noticed during COVID-19 work-up. Fine core needle biopsy of the mass led to the diagnosis of a germ cell tumor, which was treated appropriately. This study shows the importance of proper work-up in pericardial effusion cases with chest CT-scan as an important part of it.

Implication for health policy/practice/research/medical education:

The patient had massive pericardial effusion. A mediastinal mass measuring 173×105×105 mm was accidentally noticed, which led to the diagnosis of a germ cell tumor. This study shows the importance of proper work-up in pericardial effusion cases with chest CT-scan as an important part of it.

Please cite this paper as: Beheshti Monfared M, Ghaderi H, Ansari Aval Z, Hekmat M, Mirjafari SA, Beheshti Monfared R. A rare presentation of extragonadal germ cell tumor; massive pericardial effusion with impending tamponade. J Nephropathol. 2022;11(x):exx. DOI: 10.34172/ jnp.2022.xx.

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Submitted: 20 Apr 2021
Accepted: 27 Aug 2021
ePublished: 14 Dec 2021
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