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J Nephropathol. Inpress.
doi: 10.34172/jnp.2022.17337
  Abstract View: 896

Case Report

Membranous nephropathy with collapse in a HIV negative patient; a case report with a 34-month follow-up

Luisa Lemos Costa 1* ORCID logo, Ana Isabel Rodrigues 1 ORCID logo, Carolina Ferreira 1 ORCID logo, Carla Pereira Lima 1 ORCID logo, Tânia Couto Sousa 1 ORCID logo, Helena Viana 2 ORCID logo, Mário Góis 2 ORCID logo, Sérgio Silva Lemos 1 ORCID logo

1 Nephrology Department, Centro Hospitalar Tondela Viseu, Viseu, Portugal
2 Nephrology Department, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal
*Corresponding Author: *Corresponding author: Luisa Lemos Costa, Email: luisalemosccosta@gmail.com, , Email: 7886@hstviseu.min-saude.pt

Abstract

Membranous nephropathy (MN) is a common cause of nephrotic syndrome (NS) in nondiabetic adults. Collapsing nephropathy (CN) is a morphological pattern that is usually classified as a variant of focal segmental glomerulosclerosis (cFSGS). The simultaneous presence of both MN and CN is rare and their combination usually foresees an unfavorable outcome. Herein, we describe a case report of a patient with PLA2 R-associated MN with collapse, its treatment and clinical course.

Implication for health policy/practice/research/medical education:

The coexistence of CN and MN is a rare finding. This case highlights its difficult management and the potential benefit of rituximab administration in this rare entity of kidney disease.

Please cite this paper as: Costa LL, Rodrigues AI, Ferreira C, Lima CP, Sousa TC, Viana H, Góis M, Lemos SS. Membranous nephropathy with collapse in a HIV negative patient; a case report with a 34-month follow-up. J Nephropathol. 2022;11(x):exx. DOI: 10.34172/ jnp.2022.xx.

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Submitted: 14 Dec 2021
Accepted: 09 Jan 2022
ePublished: 30 Jan 2022
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