Gulcin Kantarci
1* 
, Ezgi Hacihasanoglu
2 , Alphan Sekuri
1 , Batuhan Oguz
1 , Senay Acikel
1 1 Yeditepe University, School of Medicine, Department of Nephrology and Internal Medicine, Istanbul, Turkey
2 Yeditepe University, School of Medicine, Department of Pathology, Istanbul, Turkey
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease-19 (COVID-19), still affects the world, as studies for vaccinations and treatments continue. One of the many types of COVID-19 vaccines is the messenger RNA (mRNA) vaccine. Several side effects of this type of vaccine have been reported in the literature, including renal complications. However, acute tubulointerstitial nephritis (ATIN) is a very rare complication of COVID-19 mRNA vaccine. Here we present a 50-year-old, previously healthy female who presented with renal failure following a COVID-19 mRNA BNT162b2 (Pfizer-BioNTech) vaccination and diagnosed as ATIN in the kidney biopsy. To the best of our knowledge, only two cases of ATIN following COVID-19 vaccine have been reported and one of them had an underlying kidney disease. This is the second case of ATIN following COVID-19 vaccine in a healthy individual.
Implication for health policy/practice/research/medical education:
Side effects of COVID-19 vaccine have been reported in the literature, including renal complications. Acute tubulointerstitial nephritis (ATIN) is a very rare complication of COVID-19 mRNA vaccine. This is the second case of ATIN following COVID-19 vaccine in a healthy individual.
Please cite this paper as: Kantarci G, Hacihasanoglu E, Sekuri A, Oguz1 B, Acikel S. Acute tubulointerstitial nephritis following COVID-19 mRNA vaccine: A case report. J Nephropathol. 2022;x(x):e17369. DOI: 10.34172/jnp.2022.17369.