Hossein Emad Momtaz
*1 Division of Pediatric Nephrology, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract
Background: Oral facial digital syndrome (OFDS) is the name of a group of congenital
diseases with involvement of face, oral cavity, digits and other organs. Renal involvement
in OFD may be in form of polycystic kidney disease.
Case Presentation: This case report presents a patient with OFDS who developed end-stage
renal disease (ESRD) at age of six without evidence of renal cyst in sonography.
Conclusions: It may be recommended to evaluate and follow up renal function in children
with cleft lip and cleft palate especially when they have other anomalies such as polydactyly
and oral lesions considering possibility of OFDS.
Implication for health policy/practice/research/medical education:
Renal involvement should be considered in all patients with multiple organ anomalies, especially in patients with cleft lip, cleft
palate and polydactyly. Absence of renal cysts does not exclude kidney involvement and further follow up of patient’s growth,
urine specific gravity, renal function and other sonographic findings such as renal echogenicity may be helpful.
Please cite this paper as: Emad Momtaz H. End stage renal disease in a child with oral facial digital syndrome. J Nephropathol.
2018;7(4):293-295. DOI: 10.15171/jnp.2018.58.