Hedayat Heydarizadeh
1,2 
, Mohammad Moradi
1 , Mojtaba Zare
3 , Samaneh Tahmasebi Ghorabi
2 , Seyed Hossein Hosseini
1* 1 Department of Pediatrics, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
2 Clinical Research Development Unit, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran
3 Shiraz University of Medical Sciences, Shiraz, Iran
Abstract
Familial Mediterranean fever (FMF) is an inherited disease characterized by fever and intermittent abdominal pain. Due to amyloid deposits in the kidneys and gastrointestinal tract, untreated FMF can lead to severe complications such as end-stage renal disease and malabsorption. The present study reports two brothers aged seven and five years, who presented with fever, abdominal pain, and anorexia. Based on their clinical history and ruling out other possible diagnoses, FMF was definitively diagnosed, and both patients underwent colchicine treatment.
Implication for health policy/practice/research/medical education:
The present study reports two brothers, aged seven and five years old, who presented with intermittent fever, abdominal pain, and anorexia during the last two years. Based on their clinical history and ruling out other possible diagnoses, familial Mediterranean fever was definitively diagnosed, and both patients were successfully controlled with colchicine.
Please cite this paper as: Heydarizadeh H, Moradi M, Zare M, Tahmasebi Ghorabi S, Hosseini SH. Familial Mediterranean fever in two brothers aged seven and five years old. J Nephropathol. 2025;14(1):e21505. DOI: 10.34172/jnp.2024.21505.