Logo-jnp
J Nephropathol. 2024;13(4): e21528.
doi: 10.34172/jnp.2024.21528

Scopus ID: 85202559516
  Abstract View: 329
  PDF Download: 100

Min-Review

Lupus-associated collapsing glomerulopathy; a current data

Narges Ansari 1 ORCID logo, Mansour Salesi 2* ORCID logo

1 Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Department of Rheumatology, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding Author: Mansour Salesi, Email: salesi@med.mui.ac.ir, Email: mansour1380@yahoo.com

Abstract

Collapsing glomerulopathy is a rare but severe form of glomerular injury that can be accompanying by SLE (systemic lupus erythematosus). The pathogenesis of collapsing glomerulopathy in lupus is not well understood, and the treatment options are limited. The treatment of collapsing glomerulopathy in lupus is challenging. Immunosuppressive therapy with corticosteroids and cytotoxic agents is the mainstay of treatment. However, the response to therapy is often poor, and many patients progress to end-stage renal disease despite treatment. The use of newer agents such as rituximab and belimumab may offer additional options for the treatment of collapsing glomerulopathy in lupus. Further studies are required to better detect the underlying mechanisms of collapsing glomerulopathy in lupus and to develop more effective therapies for this condition.

Implication for health policy/practice/research/medical education:

Collapsing glomerulopathy in lupus nephritis is associated with poor prognosis and rapid progression to end-stage renal disease.

Please cite this paper as: Ansari N, Salesi M. Lupus-associated collapsing glomerulopathy; a current data. J Nephropathol. 2024;13(4):e21528. DOI: 10.34172/jnp.2024.21528.

First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 330

Your browser does not support the canvas element.


PDF Download: 100

Your browser does not support the canvas element.

Submitted: 11 Nov 2023
Accepted: 17 Dec 2023
ePublished: 24 Jun 2024
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)