Mozhgan Dahmardnezhad
1 
, Tina Foodeh
2, Sholeh Afshinpoor
3, Nastaran Fooladivanda
3* 1 School of Medicine, Arak University of Medical Sciences, Arak, Iran
2 Department of Pathology, Isfahan University of Medical Sciences, Isfahan, Iran
3 Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Abstract
Cancer-associated glomerulopathy (CAG) is a rare type of glomerular disease and a complication of malignancy. It is not absolutely related to the tumor burden, invasion, or metastasis however is supposed to be caused by tumor cell products. The recognition of cancer-related glomerulopathy is clinically crucial because it can be the first sign of an underlying malignancy. The most common glomerular diseases which are caused by malignancy are paraneoplastic glomerulopathy. Moreover, membranous nephropathy is the most common glomerular pathology associated with solid tumors.
Implication for health policy/practice/research/medical education:
Cancer-associated glomerulopathy (CAG) is a rare kidney disorder that occurs in patients with cancer. It is characterized by proteinuria, hematuria, and nephrotic syndrome. The pathogenesis of cancer-related glomerulopathy is believed to be associated with the production of tumor-associated factors that affect the glomerular basement membrane and podocytes.
Please cite this paper as: Dahmardnezhad M, Foodeh T, Afshinpoor S, Fooladivanda N. Cancer-associated glomerulopathy; an updated review on current knowledge. J Nephropathol. 2024;13(2):e22539. DOI: 10.34172/jnp.2024.22539.