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J Nephropathol. 2024;13(4): e25550.
doi: 10.34172/jnp.2024.25550

Scopus ID: 85202569622
  Abstract View: 183
  PDF Download: 81

Case Report

Light chain deposition disease as monoclonal gammopathy of renal significance-a rare disease with scarce therapy; a case report

Fereshteh Saddadi 1 ORCID logo, Bahareh Marghoob 1* ORCID logo, Mohamadhasan Fallahkohan 2 ORCID logo

1 Hashemi Nejad Kidney Center (HKC), Iran University of Medical Sciences (IUMS), Tehran, Iran
2 Shahid Beheshti Medical University (SBMU), Tehran, Iran
*Corresponding Author: Bahareh Marghoob, Email: baharehmarghoob@yahoo.com

Abstract

The kidneys are one of the main organs which involved in light chain deposition disease (LCDD). The usual renal presentations are renal failure with or without nephrotic range proteinuria and microscopic hematuria. There is not a standard therapy of kidney involvement in this disease which named as monoclonal gammopathy of renal significance (MGRS). The present case is focused on a new therapeutic strategy.

Implication for health policy/practice/research/medical education:

Monoclonal gammopathy of renal significance is a new diagnostic terminology which demonstrates patients with kidney disease due to monoclonal proteins whose clinical course does not fulfill the criteria for multiple myeloma.

Please cite this paper as: Saddadi F, Marghoob B, Fallahkohan M. Light chain deposition disease as monoclonal gammopathy of renal significance-a rare disease with scarce therapy; a case report. J Nephropathol. 2024;13(4):e25550. DOI: 10.34172/jnp.2024.25550.

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Submitted: 09 May 2024
Accepted: 06 Jul 2024
ePublished: 10 Aug 2024
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