Francesco Fortarezza
1*, Maria Grazia Fiore
1, Michele Rossini
2, Domenico Piscitelli
1, Loreto Gesualdo
2, Leonardo Resta
1, Roberta Rossi
11 Department of Emergency and Organ Transplantation , Pathology Division, Medical School, University of Bari, Bari, Italy
2 Department of Emergency and Organ Transplantation, Nephrology Division, Medical School, University of Bari, Bari, Italy
Implication for health policy/practice/research/medical education:
Minimal change disease (MCD) is a disorder affecting the kidneys which causes a nephrotic
syndrome. The pathogenesis is unclear and genetic, immunological factors and infections have been
studied as a possible trigger. We describe a case of steroid-resistent MCD with an unusual pattern
of podocyte damage, occurred in children with coeliac disease, CMV infection and a variant in
heterozygosis for the ACTN4 gene.
Please cite this paper as: Fortarezza F, Fiore MG, Rossini M, Piscitelli D, Gesualdo L, Resta L, et al.
Steroid-resistant minimal change disease with ballooned podocytes. J Nephropathol. 2019;8(2):e19.
DOI: 10.15171/jnp.2019.19.