Mojgan Jahantigh
1 
, Mahsa Rezaee
2 , Moein Daneshmand
3 , Maede Karimian
4 , Mahshad Ghezelbash
5 , Behrooz Fakhar
6 , Alireza Shakeri
7* 1 Department of Community Nursing, Nursing Research Center, School of Nursing and Midwifery, Zahedan University of Medical Sciences, Zahedan, Iran
2 Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Chronic Respiratory Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Department of Anesthesiology, School of Medicine, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
5 Department of Anesthesiology, Valiasr Hospital, School of Medicine, Arak University of Medical Sciences, Arak, Iran
6 Department of Anesthesia and Intensive Care, Faculty of Medicine, Aja University of Medical Sciences, Tehran, Iran
7 Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract
Acute kidney injury (AKI) is a common and critical condition faced by patients in the intensive care units (ICUs), which significantly increases morbidity and mortality rates among affected individuals. Additionally, individuals in the ICU often present with a multitude of comorbidities, which significantly influence the risk of developing acute renal failure and the associated mortality rates. Common underlying conditions such as hypertension, diabetes, heart disease, and chronic kidney disease (CKD) predispose patients to acute renal failure. Hypertension and diabetes are particularly noteworthy as they distort renal hemodynamics, leading to increased susceptibility to acute renal failure during critical illness. Moreover, older patients consistently exhibit higher mortality rates associated with AKI, as advancing age correlates with deteriorating organ function and increased prevalence of comorbid conditions.
Implication for health policy/practice/research/medical education:
Acute kidney injury (AKI) is a critical condition frequently encountered in intensive care unit patients. Its complexity stems from a combination of underlying illnesses, the severity of the critical condition, and various precipitating factors that contribute significantly to mortality.
Please cite this paper as: Jahantigh M, Rezaee M, Daneshmand M, Karimian M, Ghezelbash M, Fakhar B, Shakeri A. Precipitating factors for mortality of individuals with acute kidney injury in ICU; collaboration of nephrologists and intensivists. J Nephropathol. 2025;14(2):e27612. DOI: 10.34172/jnp.2025.27612.