Logo-jnp
J Nephropathol. 2022;11(1): e5.
doi: 10.34172/jnp.2022.05
  Abstract View: 30
  PDF Download: 17

Original Article

Acute kidney injury after cardiac surgery in the North of Iran

Jalal Kheirkhah ORCID logo, Zahra Ahmadnia, Arsalan Salari, Heidar Dadkhah, Seyedeh Shiva Modallalkar, Tolou Hasandokht * ORCID logo

1 Cardiovascular Diseases Research Center, Department of Cardiology, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
*Corresponding author: Tolou Hasandokht, Email: Tolou.hasandokht@gmail.com, Tolou.hasandokht@gums.ac.ir

Abstract

Introduction: Acute renal failure is a well-known complication in patients after cardiac surgery.

Objectives: The determination of disease-causing factors with the aim of identifying patients at high-risk and implementing preventive care pre- and postoperatively to reduce the incidence of acute kidney injury (AKI) in patients after cardiac surgery.

Patients and Methods: The present cross-sectional research was carried out on 512 adult patients who underwent cardiac surgery between 2015 and 2016 in our tertiary center. Demographic and laboratory data of patients were obtained using a checklist. AKI is defined as an increase of at least 0.3 mg/dL in creatinine (Cr) over 48 hours and one week after surgery according to acute kidney injury network (AKIN) and RIFLE (risk, injury, failure, loss of kidney function, and end-stage renal failure) criteria before surgery. All data were analyzed by SPSS version 1, and P value <0.05 was considered significant.

Results: In this study we found, AKI risk profiles including serum Cr level [OR = 3.24, 95% CI = 1.92 -12.48, P = 0.001], fasting blood glucose [OR = 1.22, 95% CI = 1.09 -1.92, P = 0.03] and hemoglobin (Hb) before surgery (OR = 0.59, 95% CI = 0.08 -0.87, P = 0.04) were significantly associated with increased risk of acute renal injury (logistic regression analysis).

Conclusion: The results indicated that changes in serum Cr level, fasting blood glucose and plasma Hb before cardiac surgery might be considered as the risk factors for AKI after cardiac surgery.


Keywords: Kidney, Injuryy, Risk factors, Serum creatinine, Cardiac surgery, Acute kidney injury, Renal replacement therapy

Implication for health policy/practice/research/medical education:

Identifying patients at high-risk and implementing preventive care pre- and postoperatively to reduce the incidence of acute kidney injury in patients after cardiac surgery, we conducted a study on 512 adult patients who underwent cardiac surgery. Our results indicated that changes in serum creatinine level, fasting blood glucose and hemoglobin levels before cardiac surgery may be considered as the risk factors for acute kidney injury after cardiac surgery.

Please cite this paper as: Kheirkhah J, Ahmadnia Z, Salari A, Dadkhah H, Modallalkar SS, Hasandokht T. Acute kidney injury after cardiac surgery in the North of Iran. J Nephropathol. 2022;11(1):e05. doi: 10.34172/jnp.2022.05.


First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 30

Your browser does not support the canvas element.


PDF Download: 17

Your browser does not support the canvas element.

Submitted: 18 Oct 2019
Accepted: 02 Feb 2020
ePublished: 18 Feb 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)