Society of Diabetic Nephropathy Prevention Journal of Nephropathology 2251-8363 12 1 2023 01 01 Prevalence of hyponatremia in hospitalized patients with coronavirus disease 2019; a multicenter study e18383 e18383 10.34172/jnp.2022.18383 EN Sepideh Hajian https://orcid.org/0000-0001-5404-2765 Ali Sarbazi-Golezari https://orcid.org/0000-0002-4570-5472 Maryam Karbasi https://orcid.org/0000-0003-4545-6143 Journal Article 10.34172/jnp.2022.18383 2022 01 10 2022 05 07 Introduction: In patients with coronavirus disease 2019 (COVID-19), the prevalence of hyponatremia has been reported with varying outcomes. Objectives: The aim of this study was to evaluate the prevalence of hyponatremia in hospitalized patients with COVID-19. Patients and Methods: In this multicenter cross-sectional study, information about hospitalized patients with COVID-19 admitted between March 2020 and September 2020, including age, gender, and serum levels of sodium, creatinine, and potassium, as well as blood urea nitrogen (BUN), was analyzed, while P value level less than 0.05 was considered significant. Results: A total of 667 hospitalized patients with COVID-19 were enrolled in the study, of which 54.4% were male. The median age of patients was 63 years old. About 39.4% of patients had hyponatremia on admission day. More than 80% of patients had mild hyponatremia. The median age of the hyponatremia group was significantly higher than that of eunatremia group. Conclusion: Our data showed that hyponatremia is observed in hospitalized patients with COVID-19 and is often mild.