﻿<?xml version="1.0" encoding="UTF-8"?>
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>Society of Diabetic Nephropathy Prevention</PublisherName>
      <JournalTitle>Journal of Nephropathology</JournalTitle>
      <Issn>2251-8363</Issn>
      <Volume>12</Volume>
      <Issue>4</Issue>
      <PubDate PubStatus="ppublish">
        <Year>2023</Year>
        <Month>09</Month>
        <DAY>19</DAY>
      </PubDate>
    </Journal>
    <ArticleTitle>Advances in IgA nephropathy management, from pathological insights to personalized treatment</ArticleTitle>
    <FirstPage>e21480</FirstPage>
    <LastPage>e21480</LastPage>
    <ELocationID EIdType="doi">10.34172/jnp.2023.21480</ELocationID>
    <Language>EN</Language>
    <AuthorList>
      <Author>
        <FirstName>Mitra</FirstName>
        <LastName>Shavakhi</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0003-0719-0786</Identifier>
      </Author>
      <Author>
        <FirstName>Agha Wajdan</FirstName>
        <LastName>Baqir</LastName>
        <Identifier Source="ORCID">https://orcid.org/0000-0002-1158-8896</Identifier>
      </Author>
    </AuthorList>
    <PublicationType>Journal Article</PublicationType>
    <ArticleIdList>
      <ArticleId IdType="doi">10.34172/jnp.2023.21480</ArticleId>
    </ArticleIdList>
    <History>
      <PubDate PubStatus="received">
        <Year>2023</Year>
        <Month>04</Month>
        <Day>26</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2023</Year>
        <Month>06</Month>
        <Day>21</Day>
      </PubDate>
    </History>
    <Abstract>IgA nephropathy is a common glomerulonephritis with variable clinical outcomes. The optimal treatment for this condition remains uncertain, and corticosteroid therapy is reserved for patients unresponsive to supportive treatment. The histopathologic examination has a significant role in the diagnosis and prognosis of IgA nephropathy, but its role in the initiation of corticosteroid therapy is still under debate. Recently, targeted release formulation (TRF)-budesonide has emerged as a promising treatment due to its localized delivery to the gut and low systemic adverse effects. This brief review aims to assess recent advancements in IgA nephropathy management, focusing on applying Oxford classification in guiding corticosteroid therapy.</Abstract>
    <ObjectList>
      <Object Type="keyword">
        <Param Name="value">IgA nephropathy</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Targeted-release budesonide</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Corticosteroid</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Oxford classification</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">MEST-C score</Param>
      </Object>
    </ObjectList>
  </Article>
</ArticleSet>