Society of Diabetic Nephropathy Prevention Journal of Nephropathology 2251-8363 14 2 2025 04 01 Precipitating factors for mortality of individuals with acute kidney injury in ICU; collaboration of nephrologists and intensivists e27612 e27612 10.34172/jnp.2025.27612 EN Mojgan Jahantigh https://orcid.org/0000-0002-9208-1404 Mahsa Rezaee https://orcid.org/0009-0005-3094-0874 Moein Daneshmand https://orcid.org/0000-0003-3828-9578 Maede Karimian https://orcid.org/0000-0003-4854-7470 Mahshad Ghezelbash https://orcid.org/0009-0003-7246-1172 Behrooz Fakhar https://orcid.org/0000-0003-0659-3583 Alireza Shakeri https://orcid.org/0000-0001-8095-7168 Journal Article 10.34172/jnp.2025.27612 2024 11 19 2025 02 08 Acute kidney injury (AKI) is a common and critical condition faced by patients in the intensive care units (ICUs), which significantly increases morbidity and mortality rates among affected individuals. Additionally, individuals in the ICU often present with a multitude of comorbidities, which significantly influence the risk of developing acute renal failure and the associated mortality rates. Common underlying conditions such as hypertension, diabetes, heart disease, and chronic kidney disease (CKD) predispose patients to acute renal failure. Hypertension and diabetes are particularly noteworthy as they distort renal hemodynamics, leading to increased susceptibility to acute renal failure during critical illness. Moreover, older patients consistently exhibit higher mortality rates associated with AKI, as advancing age correlates with deteriorating organ function and increased prevalence of comorbid conditions.