Society of Diabetic Nephropathy Prevention Journal of Nephropathology 2251-8363 9 2 2020 04 01 Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder e20 e20 10.34172/jnp.2020.20 EN Paulette Cutruzzula Dreher https://orcid.org/0000-0002-1931-8735 Jessica M. Fazendin https://orcid.org/0000-0003-2246-5055 Kelly Lurz https://orcid.org/0000-0002-3855-4450 Daniel C. Edwards https://orcid.org/0000-0002-4978-7460 Stephen Guy https://orcid.org/0000-0002-1658-7921 Melanie Amster https://orcid.org/0000-0001-9342-7254 Journal Article 10.34172/jnp.2020.20 2018 05 06 2019 07 27 Introduction: There exist few reports of de novo tumors involving an allograft kidney, and to the best of our knowledge there are only two previous reports of angiomyxoma Case Presentation: A 53-year-old Caucasian male with end-stage renal disease (ESRD) on hemodialysis (HD) secondary to malakoplakia with three failed prior renal transplants presented for repeat transplant evaluation. Imaging demonstrated a mass of the transplanted kidney suggestive of posttransplant lymphoproliferative disease (PTLPD). A biopsy was obtained revealing a predominance of myxoid material. The patient became increasingly symptomatic from the mass and underwent a palliative right transplant nephrectomy. Final pathology revealed angiomyxoid tumor. Conclusions: Angiomyxomas are asymptomatic, appear as PTLD on imaging and should be considered in the differential diagnosis of masses occurring in renal transplant allografts.