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J Nephropathol. 2016;5(1): 38-43. doi: 10.15171/jnp.2016.07
PMID: 27047809        PMCID: PMC4790186

Original Article

Effects of coenzyme Q10 supplementation on C-reactive protein and homocysteine as the inflammatory markers in hemodialysis patients; a randomized clinical trial

Narges-Sadat Zahed 1, Maryam Ghassami 2 * , Hajar Nikbakht 1

Cited by CrossRef: 16

1- Martelli A, Testai L, Colletti A, Cicero A. Coenzyme Q10: Clinical Applications in Cardiovascular Diseases. Antioxidants. 2020;9(4):341 [Crossref]
2- Gao J, Xu Y, Jia H, Zhang L, Cao X, Zuo X, Cai G, Chen X. Associations of coenzyme Q10 with endothelial function in hemodialysis patients. Nephrology. 2021;26(1):54 [Crossref]
3- Mantle D, Hargreaves I. Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview. Antioxidants. 2019;8(2):44 [Crossref]
4- Xu Y, Yang G, Zuo X, Gao J, Jia H, Han E, Liu J, Wang Y, Yan H. A systematic review for the efficacy of coenzyme Q10 in patients with chronic kidney disease. Int Urol Nephrol. 2022;54(1):173 [Crossref]
5- Gromova O, Torshin I, Gromov A. Possibilities of using coenzyme Q10 for the treatment of diseases associated with mitochondrial dysfunction and chronic inflammation. Farmakoèkonomika. 2023;16(3):466 [Crossref]
6- Hargreaves I, Mantle D, Milford D. Chronic kidney disease and coenzyme Q10 supplementation. Journal of Kidney Care. 2019;4(2):82 [Crossref]
7- Ju W, Li X, Li Z, Wu G, Fu X, Yang X, Zhang X, Gao X. The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials. Journal of Trace Elements in Medicine and Biology. 2017;44:8 [Crossref]
8- Fan L, Feng Y, Chen G, Qin L, Fu C, Chen L. Effects of coenzyme Q10 supplementation on inflammatory markers: A systematic review and meta-analysis of randomized controlled trials. Pharmacological Research. 2017;119:128 [Crossref]
9- Fallah M, Askari G, Soleimani A, Feizi A, Asemi Z. Clinical trial of the effects of coenzyme Q10 supplementation on glycemic control and markers of lipid profiles in diabetic hemodialysis patients. Int Urol Nephrol. 2018;50(11):2073 [Crossref]
10- Sharaf S, Fahmy S, Abou Zaghla H, Hassan A, Zaki S. Evaluation of efficacy and safety of coenzyme Q10 in pediatric hemodialysis patients: a randomized controlled trial. Futur J Pharm Sci. 2025;11(1) [Crossref]
11- Zhao M, Tian Z, Zhao D, Liang Y, Dai S, Xu Y, Hou S, Yang Y. L-shaped association between dietary coenzyme Q10 intake and high-sensitivity C-reactive protein in Chinese adults: a national cross-sectional study. Food Funct. 2023;14(21):9815 [Crossref]
12- YUMUŞAK N, KOCA G, AKBULUT A, ATILGAN H, KORKMAZ M. Proliferative and apoptotic evaluations of renal preventive effects of coenzyme Q10 in radioiodine-131 induced renal damage. 2022;69(3):265 [Crossref]
13- AHMED N, SABRA H. Alpha lipoic acid and green tea extract with oral antidiabetic therapy ameliorate hepatic damage in streptozotocin induced diabetic rats. Int J Pharma Bio Sci. 2018;9(2) [Crossref]
14- Hou S, Tian Z, Zhao D, Liang Y, Dai S, Ji Q, Fan Z, Liu Z, Liu M, Yang Y. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation‐Related Biomarkers: A GRADE‐Assessed Systematic Review and Updated Meta‐Analysis of Randomized Controlled Trials. Molecular Nutrition Food Res. 2023;67(13) [Crossref]
15- Colombijn J, Hooft L, Jun M, Webster A, Bots M, Verhaar M, Vernooij R. Antioxidants for adults with chronic kidney disease. 2023;2023(11) [Crossref]
16- Mantle D. Home haemodialysis. Journal of Kidney Care. 2019;4(5):238 [Crossref]
17- Shahraki E, Shahraki B, Dashipour A. Non-traditional Risk Factors of Cardiovascular Disease and Coenzyme Q10 Therapy in Hemodialysis Patients. Nephro-Urol Mon. 2021;13(1) [Crossref]