Simvastatin attenuates chromium-induced nephrotoxicity in rats

Zahra Goodarzi ¹, Esmaeil Karami ¹, Massumeh Ahmadizadeh ^2,3 *

Cited by CrossRef: 11

1- El-Demerdash F, El-Sayed R, Abdel-Daim M. Rosmarinus officinalis essential oil modulates renal toxicity and oxidative stress induced by potassium dichromate in rats. Journal of Trace Elements in Medicine and Biology. 2021;67:126791 [Crossref]

2- Okail H, Anjum S, Emam N, Abdel‐Gaber R, Dkhil M, El‐Ashram S, Ibrahim M. Ameliorative effect of aqueous avocado seed extract against chromium‐induced oxidative stress and cellular damage in rabbit kidney. Food Science & Nutrition. 2024;12(8):5799 [Crossref]

3- Savici J, Boldura O, Balta C, Muselin F, Mederle N, Cristina R, Brezovan D. Effects of Aronia melanocarpa and Hypericum perforatum aqueous extracts on hexavalent chromium induced toxicity in rat’s thyrocytes. Journal of Trace Elements in Medicine and Biology. 2023;78:127151 [Crossref]

4- Karami E, Goodarzi Z, Ghanbari A, Bandegi A, Yosefi S, Dehdashti A. In vivo antioxidant and kidney protective potential of Atorvastatin against cadmium chloride-induced kidney injury in male Wistar rat. All Life. 2022;15(1):1025 [Crossref]

5- Fedala A, Adjroud O, Bennoune O, Abid-Essefi S, Foughalia A, Timoumi R. Nephroprotective Efficacy of Selenium and Zinc Against Potassium Dichromate-Induced Renal Toxicity in Pregnant Wistar Albino Rats. Biol Trace Elem Res. 2022;200(11):4782 [Crossref]

6- Mitra S, Chakraborty A, Tareq A, Emran T, Nainu F, Khusro A, Idris A, Khandaker M, Osman H, Alhumaydhi F, Simal-Gandara J. Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity. Journal of King Saud University - Science. 2022;34(3):101865 [Crossref]

7- Fu S, Liu J, Lee K, Tang F, Fang K, Yang C, Su C, Chen H, Hsu R, Chen Y. Cr(VI) induces ROS-mediated mitochondrial-dependent apoptosis in neuronal cells via the activation of Akt/ERK/AMPK signaling pathway. Toxicology in Vitro. 2020;65:104795 [Crossref]

8- Karami E, Goodarzi Z, Ghanbari A, Dehdashti A, Bandegi A, Yosefi S. Atorvastatin prevents cadmium-induced renal toxicity in a rat model. Toxicol Ind Health. 2023;39(4):218 [Crossref]

9- Fedala A, Adjroud O, Abid-Essefi S, Timoumi R. Protective effects of selenium and zinc against potassium dichromate–induced thyroid disruption, oxidative stress, and DNA damage in pregnant Wistar rats. Environ Sci Pollut Res. 2021;28(18):22563 [Crossref]

10- Alanazi S, Salama S, Althobaiti M, Almalki A, Bakhsh A, Musa A, Mohammed A. Ferulic Acid Ameliorates Chromium-Induced Nephrotoxicity: Modulation of PERK/eIF2α/ATF4/CHOP, Nrf2, and Inflammatory Signaling. Biol Trace Elem Res. 2025; [Crossref]

11- Fedala A, Adjroud O, Saouli A, Salah I. Assessment of the Protective Effects of Selenium and Zinc against Potassium Dichromate Induced Thyrotoxicity in Preimplanted Wistar albinos Rats. TI. 2023;:1 [Crossref]

12- Kurmangaliyeva S, Baktikulova K, Tkachenko V, Seitkhanova B, Shapambayev N, Rakhimzhanova F, Almagambetova A, Kurmangaliyev K. An Overview of Hexavalent Chromium-Induced Necroptosis, Pyroptosis, and Ferroptosis. Biol Trace Elem Res. 2024; [Crossref]

13- Yin F, Yan J, Zhao Y, Guo K, Zhang Z, Li A, Meng C, Guo L. Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway. Ecotoxicology and Environmental Safety. 2019;176:234 [Crossref]