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J Nephropathol. 2017;6(3): 187-195. doi: 10.15171/jnp.2017.32
PMID: 28975100        PMCID: PMC5607982

Original Article

Impact of Τh1 and Τh2 cytokines in the progression of idiopathic nephrotic syndrome due to focal segmental glomerulosclerosis and minimal change disease

Maria Stangou 1 * , Μichael Spartalis 1, Dimitra-Vasilia Daikidou 1, Theodora Kouloukourgiotou 1, Erasmia Sampani 1, Ioanna-Theologia Lambropoulou 1, Afroditi Pantzaki 2, Αikaterini Papagianni 1, George Efstratiadis 1

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2- Akl A, Fakeeh M. Long term effects of SARS-Cov2 associated minimal change glomerulonephritis: a case report and review of literature. UNOAJ. 2023;11(3):85 [Crossref]
3- Zhang Y, Lv J, Bai J, Pu X, Dai E. Identification of key biomarkers of the glomerulus in focal segmental glomerulosclerosis and their relationship with immune cell infiltration based on WGCNA and the LASSO algorithm. Renal Failure. 2023;45(1) [Crossref]
4- Seyam M, Aboazma S, Abdeen H, El-Desoky M. Uteroglobin gene polymorphism (G38A) as a potential risk factor for nephrotic syndrome in Egyptian children. Egyptian Journal of Basic and Applied Sciences. 2024;11(1):508 [Crossref]
5- Chen P, Chen Y, Jiang M, Mo Y, Ying H, Tang X, Zhang J. Usefulness of the cytokines expression of Th1/Th2/Th17 and urinary CD80 excretion in adult-onset minimal change disease. 2020;8:e9854 [Crossref]
6- Kanazawa N, Iyoda M, Suzuki T, Tachibana S, Nagashima R, Honda H. Exploring the significance of interleukin-33/ST2 axis in minimal change disease. Sci Rep. 2023;13(1) [Crossref]
7- Low L, Lu L, Chan C, Chen J, Yang H, Yu H, Lee C, Ng K, Yap H. IL-13-driven alterations in hepatic cholesterol handling contributes to hypercholesterolemia in a rat model of minimal change disease. 2020;134(2):225 [Crossref]
8- Zununi Vahed S, Hosseiniyan Khatibi S, Ardalan M. Canonical effects of cytokines on glomerulonephritis: A new outlook in nephrology. Medicinal Research Reviews. 2025;45(1):144 [Crossref]
9- Salfi G, Casiraghi F, Remuzzi G. Current understanding of the molecular mechanisms of circulating permeability factor in focal segmental glomerulosclerosis. Front Immunol. 2023;14 [Crossref]
10- Liu J, Guan F. B cell phenotype, activity, and function in idiopathic nephrotic syndrome. Pediatr Res. 2023;93(7):1828 [Crossref]
11- Oshima Y, Sumida K, Yamanouchi M, Hayami N, Sekine A, Mizuno H, Kawada M, Hiramatsu R, Hasegawa E, Suwabe T, Hoshino J, Sawa N, Fujii T, Takaichi K, Ubara Y. Corticosteroid reduction by addition of cetirizine and montelukast in biopsy-proven minimal-change nephrotic syndrome concomitant with allergic disorders. Sci Rep. 2020;10(1) [Crossref]
12- Romanova Y, Laikov A, Markelova M, Khadiullina R, Makseev A, Hasanova M, Rizvanov A, Khaiboullina S, Salafutdinov I. Proteomic Analysis of Human Serum from Patients with Chronic Kidney Disease. Biomolecules. 2020;10(2):257 [Crossref]
13- Mirza A, Kowalewska J, McCune T. Transplantation With APOL1 Risk Variant Kidney May Be Associated With Lifetime Risk for Recurrence of Focal Segmental Glomerulosclerosis: A Case Report and Review of Literature. Transplantation Proceedings. 2019;51(9):3077 [Crossref]
14- Yamada M, Rastogi P, Ince D, Thayyil A, Adela Mansilla M, Smith R, Kuppachi S, Thomas C. Minimal Change Disease With Nephrotic Syndrome Associated With Coronavirus Disease 2019 After Apolipoprotein L1 Risk Variant Kidney Transplant: A Case Report. Transplantation Proceedings. 2020;52(9):2693 [Crossref]
15- Stenvinkel P, Chertow G, Devarajan P, Levin A, Andreoli S, Bangalore S, Warady B. Chronic Inflammation in Chronic Kidney Disease Progression: Role of Nrf2. Kidney International Reports. 2021;6(7):1775 [Crossref]
16- Kitsou K, Askiti V, Mitsioni A, Spoulou V. The immunopathogenesis of idiopathic nephrotic syndrome: a narrative review of the literature. Eur J Pediatr. 2022;181(4):1395 [Crossref]