Logo-jnp
J Nephropathol. 2021;10(4): e36.
doi: 10.34172/jnp.2021.36
  Abstract View: 179
  PDF Download: 115

Editorial

Hyperoxaluria; a risk factor or a consequence of recurrent pyelonephritis?

Natalia Stepanova 1 * ORCID logo

1 State Institution “Institute of Nephrology of the National Academy of Medical Sciences”, Kyiv, Ukraine
*Corresponding author: Prof. Natalia Stepanova, MD, Email: nmstep88@gmail.com, director@inephrology.kiev.ua
Keywords: Hyperoxaluria, pyelonephritis, gut microbiota

Implication for health policy/practice/research/medical education:

Hyperoxaluria often coexists with recurrent pyelonephritis which may be caused by the destruction of the gut microbiota. It would be logical to assume the formation of a so-called “vicious circle”. On the one hand, the development of dysbiosis and intestinal barrier dysfunction, mediated by the constant use of antibiotics, are the main sources of urinary tract infection; while they lead to impaired oxalate transport and acquired hyperoxaluria. In turn, calcium oxalate deposition in the proximal renal tubules causes chronic inflammation and might be an independent risk factor for pyelonephritis recurrences. Further studies are needed to clarify the mechanism of this interaction.

Please cite this paper as: Stepanova N. Hyperoxaluria; a risk factor or a consequence of recurrent pyelonephritis? J Nephropathol. 2021;10(4):e36. DOI: 10.34172/jnp.2021.36.

First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 179

Your browser does not support the canvas element.


PDF Download: 115

Your browser does not support the canvas element.

Submitted: 05 Apr 2020
Accepted: 31 Jul 2020
ePublished: 13 Aug 2020
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)