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J Nephropathol. 2022;11(4): e17322.
doi: 10.34172/jnp.2022.17322
  Abstract View: 114
  PDF Download: 21

Original Article

Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers

Seyyedeh Sahereh Mortazavi Khatibani ORCID logo, Maryam Yaseri ORCID logo, Haniyeh Sadat Fayazi* ORCID logo, Elham Ramzanzadeh ORCID logo, Azin Hajipoor ORCID logo

1 Assistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
*Corresponding Author: Corresponding author: Haniyeh Sadat Fayazi, Email: fayazihaniyehsadat@gmail.com, , Email: h.fayazi@gums.ac.ir

Abstract

Introduction: Adequate and effective dialysis can improve patients’ quality of life and reduce kidney failure complications and mortality in end-stage renal disease on hemodialysis.

Objectives: This study aimed to evaluate dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis.

Patients and Methods: This cross-sectional, multi-center study was conducted during six months on hemodialysis patients referred to dialysis centers of the Guilan province in the north of Iran. Dialysis adequacy was evaluated using Kt/V (>1.2) criteria.

Results: The mean Kt/V was 1.24±0.36 with a median of 1.2. Adequacy of dialysis was desirable in 51.2% of the patients. There was a significant and inverse relationship between body mass index (BMI) and Kt/V (r=-0.139, P=0.013). The relationship between Kt/V criterion and pre-dialysis weight (r=-0.310, P=0.00) and post-dialysis weight (r=-0.314, P=0.00) were inverse. The Kt/V criterion was significantly associated with calcium (Ca) level and the patients with normal Ca level had a higher adequacy than those in the other levels of Ca [normal versus low level, mean difference (MD]: 0.19±0.06; normal versus high level, MD: 0.07±0.04, P<0.001). The Kt/V criterion was inversely related to blood pressure and temperature before and after dialysis (P<0.05).

Conclusion: The present study showed a close correlation between blood pressure, Ca level and BMI with dialysis adequacy based on Kt/V criteria. The findings obtained here suggested treatment strategies based on correction of Ca levels, BMI and blood pressure prior to dialysis to increase the adequacy of dialysis.


Implication for health policy/practice/research/medical education:

In a cross-sectional, multi-center study on hemodialysis patients in the north of Iran, we found a significant positive relationship between the years of dialysis and Kt/V dialysis adequacy (r=0.131).

Please cite this paper as: Mortazavi Khatibani SS, Yaseri M, Fayazi HS, Ramzanzadeh ER, Hajipoor A. Evaluation of dialysis adequacy based on Kt/V and its related factors among patients undergoing hemodialysis in Guilan dialysis centers. J Nephropathol. 2022;11(4):e17322. DOI: 10.34172/jnp.2022.17322.

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Submitted: 30 Nov 2021
Accepted: 11 Feb 2022
ePublished: 20 Feb 2022
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