Paulette Cutruzzula Dreher
1* 
, Jessica M. Fazendin
2 , Kelly Lurz
1,2 , Daniel C. Edwards
1 , Stephen Guy
1 , Melanie Amster
1 1 Department of Urology, Hahnemann University Hospital, Philadelphia, PA, USA
2 Department of General Surgery, Drexel University College of Medicine, Philadelphia, PA, USA
3 Department of Transplant Surgery, Drexel University College of Medicine, Philadelphia, PA, USA
Abstract
Introduction: There exist few reports of de novo tumors involving an allograft kidney, and to the best of our knowledge there are only two previous reports of angiomyxoma
Case Presentation: A 53-year-old Caucasian male with end-stage renal disease (ESRD) on hemodialysis (HD) secondary to malakoplakia with three failed prior renal transplants presented for repeat transplant evaluation. Imaging demonstrated a mass of the transplanted kidney suggestive of posttransplant lymphoproliferative disease (PTLPD). A biopsy was obtained revealing a predominance of myxoid material. The patient became increasingly symptomatic from the mass and underwent a palliative right transplant nephrectomy. Final pathology revealed angiomyxoid tumor.
Conclusions: Angiomyxomas are asymptomatic, appear as PTLD on imaging and should be considered in the differential diagnosis of masses occurring in renal transplant allografts.
Implication for health policy/practice/research/medical education:
Allograft kidney transplant patients presenting with post-transplant lymphoproliferative disease on imaging should be considered in differential diagnosis of rare masses occurring de novo in renal transplant patients.
Please cite this paper as: Dreher PC, Fazendin JM, Lurz K, Edwards DC, Guy S, Amster M. Painful angiomyxoid tumor in a failed renal allograft presenting as post-transplant lymphoproliferative disorder. J Nephropathol. 2020;9(2):e20. DOI: 10.34172/jnp.2020.20.